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dc.contributor.authorEley, Victoriaen_US
dc.contributor.authorChin, Adrianen_US
dc.contributor.authorSekar, Renukaen_US
dc.contributor.authorDonovan, Timothyen_US
dc.contributor.authorKrepska, Amyen_US
dc.contributor.authorLawrence, Mitchellen_US
dc.contributor.authorBell, Sheridanen_US
dc.contributor.authorRalfem, Kateen_US
dc.contributor.authorMcGrath, Shaunen_US
dc.contributor.authorWebb, Lachlanen_US
dc.contributor.authorRobinson, Alexanderen_US
dc.contributor.authorvan Zundert, Andreen_US
dc.contributor.authorMarquart, Louiseen_US
dc.description.abstractBACKGROUND: Body mass index does not indicate the distribution of adipose tissue. Central adiposity may be measured using ultrasound measurement of subcutaneous fat thickness. This study determined if the abdominal subcutaneous fat thickness measured correlated with skin-to-epidural space distance at delivery, and compared this with the booking body mass index. METHODS: We analysed a sub-set of participants from a single-centre, prospective cohort study that assessed the relationship between subcutaneous fat thickness and maternity outcomes. Abdominal subcutaneous fat thickness measurements were obtained during the routine fetal anomaly scan. The skin-to-epidural space distance was obtained in those having epidural or combined spinal-epidural analgesia. Linear regression was used to test for strength of association and adjusted R2 values calculated to determine if subcutaneous fat thickness or body mass index was more strongly associated with skin-to-epidural space distance. RESULTS: The 463 women had a median (IQR) booking body mass index of 25.0 kg/m2 (21.8-29.3) and subcutaneous fat thickness of 16.2 mm (13.0-21.0). The median (IQR) skin-to-epidural space distance was 5.0 cm (4.5-6.0). Both parameters significantly correlated with skin-to-epidural space distance (r=0.53 and 0.68 respectively, P <0.001. Adjusted linear regression coefficient (95% CI) for subcutaneous fat thickness was 0.09 (0.08-0.11), R2=0.30 and for body mass index 0.12 (0.11-0.13), R2=0.47. CONCLUSIONS: Booking body mass index had a stronger relationship with skin-to-epidural space distance at delivery than subcutaneous fat thickness, explaining 47% of the variation in the skin-to-epidural distance.en_US
dc.subjectBody Mass Indexen_US
dc.subjectSubcutaneous Fat, Abdominalen_US
dc.subjectCesarean Sectionen_US
dc.subjectEpidural Spaceen_US
dc.subjectAnalgesia, Epiduralen_US
dc.titleIncreasing body mass index and abdominal subcutaneous fat thickness are associated with increased skin-to-epidural space distance in pregnant womenen_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleInternational Journal of Obstetric Anesthesiaen_US
dc.description.affiliatesThe Royal Brisbane and Women's Hospitalen_US
dc.description.affiliatesThe University of Queenslanden_US
dc.description.affiliatesQIMR Berghoferen_US
dc.type.studyortrialObservational studyen_US
dc.contributor.anzcaBell, SBen_US
dc.contributor.anzcaChin, AMen_US
dc.contributor.anzcaEley, VAen_US
dc.contributor.anzcaKrepska, ALen_US
dc.contributor.anzcaLawrence, MJen_US
dc.contributor.anzcaVan Zundert, AMen_US
Appears in Collections:Scholarly and Clinical

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