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dc.contributor.authorSoeding, PFen_US
dc.contributor.authorCurrigan, DAen_US
dc.contributor.authorMamo, Yen_US
dc.contributor.authorHoy, Gen_US
dc.description.abstractInterscalene blockade (ISB) is commonly associated with Horner's syndrome, indicating spread of injectate to the cervical sympathetic chain. Cervical sympathetic nerve activity (SNA) is believed to influence cerebral autoregulation, and a decrease in sympathetic tone may alter cerebral blood flow (CBF). This study investigated whether ISB influenced CBF in patients undergoing shoulder surgery. Patients (n=30) scheduled for elective shoulder arthroscopy were recruited. Cerebral oxygen saturation (ScO(2)) of the left and right frontal cortices was continuously measured during ISB administration, sedation and anaesthetic induction. Baseline ScO(2) was similar in blocked and unblocked sides (74 ± 5% and 73 ± 5% respectively, P=0.70). ScO(2) decreased with sedation (-3 ± 3% and -4 ± 3%, P=0.93), and increased with pre-oxygenation and general anaesthesia (P <0.01). Following ISB there was no change in ScO(2) between blocked and unblocked sides (P=0.18), or any difference between right- or left-sided ISB. ISB is not associated with an increase in CBF as indicated by ScO(2), despite the presence of Horner's syndrome.en_US
dc.subjectcerebral blood flowen_US
dc.subjectcerebral oximetryen_US
dc.subjectinterscalene blocken_US
dc.subjectCerebrovascular Circulationen_US
dc.titleEffect of interscalene anaesthesia on cerebral oxygen saturation.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleAnaesthesia and Intensive Careen_US
dc.description.affiliatesDepartment of Anaesthesia and Pain Management, Royal Melbourne Hospitalen_US
dc.description.affiliatesDepartment of Pharmacology, University of Melbourneen_US
dc.description.affiliatesDepartment of Anaesthesia and Pain Management, Royal Melbourne Hospitalen_US
dc.description.affiliatesCardiovascular Therapeutics Unit, Department of Pharmacology and Therapeutics, University of Melbourneen_US
dc.description.affiliatesMelbourne Orthopaedic Grouen_US
dc.type.studyortrialCase Control Studiesen_US
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
Appears in Collections:Scholarly and Clinical
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