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dc.contributor.authorSilbert, Brendan S-
dc.contributor.authorScott, David A-
dc.contributor.authorEvered, Lisbeth A-
dc.contributor.authorLewis, Matthew S-
dc.contributor.authorMaruff, Paul T-
dc.identifier.citationAnesthesia and analgesia 2007-05; 104(5): 1023-8, tables of contents-
dc.description.abstractAn accurate assessment of the prevalence of cognitive impairment in patients scheduled for coronary artery bypass graft (CABG) surgery is necessary if valid assumptions regarding cognitive change are to be made. Such an assessment requires the use of a healthy control group free of cardiovascular disease. In a retrospective observational study, 349 patients scheduled for CABG surgery underwent neuropsychological testing. We compared the results with those from a group of 170 healthy controls without cardiovascular disease and containing more female patients who were matched for age and IQ score. Cognitive impairment was defined as test scores > or =2 sd less than the controls on two or more of the seven tests. The CABG surgery patients performed significantly worse than the control group on all tests except the Grooved Pegboard test (nondominant). When analyzed by group, performance on the verbal learning test was the most impaired. Cognitive impairment was present in 122 (35%) of CABG surgery patients before their procedure. Prior myocardial infarction, age, and IQ were independent predictors of cognitive impairment. Cognitive impairment is prevalent in patients presenting for CABG surgery. Impaired cognition before surgery must be considered when assessing the effects of CABG surgery on cognitive performance.-
dc.subject.meshCognition Disorders-
dc.subject.meshMiddle Aged-
dc.subject.meshPreoperative Care-
dc.subject.meshRetrospective Studies-
dc.subject.meshCoronary Artery Bypass-
dc.subject.meshElective Surgical Procedures-
dc.subject.meshNeuropsychological Tests-
dc.titlePreexisting cognitive impairment in patients scheduled for elective coronary artery bypass graft surgery.-
dc.typeComparative Study-
dc.typeJournal Article-
dc.typeResearch Support, Non-U.S. Gov't-
dc.identifier.journaltitleAnesthesia and analgesia-
Appears in Collections:Scholarly and Clinical

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