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Please use this identifier to cite or link to this item: https://hdl.handle.net/11055/184
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dc.contributor.authorRamgolam, A-
dc.contributor.authorHall, G L-
dc.contributor.authorZhang, G-
dc.contributor.authorHegarty, M-
dc.contributor.authorvon Ungern Sternberg, BS-
dc.date2015-
dc.date.accessioned2018-03-08T00:19:47Z-
dc.date.available2018-03-08T00:19:47Z-
dc.date.issued2015-10-
dc.identifier.citationAnaesthesia 2015-10; 70(10): 1160-4-
dc.identifier.urihttp://hdl.handle.net/11055/184-
dc.description.abstractIncreased levels of exhaled nitric oxide (eNO) may be a more objective predictor in identifying children at higher risk of peri-operative adverse respiratory events than the presence of risk factors such as recent cold or wheeze. Children with either none or ≥ 2 risk factors had eNO measured before surgery and any peri-operative adverse respiratory events were recorded. We found that an elevated eNO level was only predictive of adverse respiratory events in children with ≥ 2 risk factors (OR 2.96 (95% CI 1.48-5.93), p = 0.002). The presence of risk factors had a better predictive capability than a raised eNO level (OR 3.83 (95% CI 1.85-7.95), p < 0.001). The combination of both predictors did not improve the predictive capability for adverse respiratory events (OR 1.93 (95% CI 1.44-2.59), p < 0.001). We conclude that measuring eNO levels does not lead to improved prediction of adverse respiratory events and that, in routine clinical practice, an accurate history of risk factors remains the most appropriate tool for successfully identifying children at risk of peri-operative adverse respiratory events.-
dc.language.isoeng-
dc.subject.meshAdolescent-
dc.subject.meshAnesthesia, General-
dc.subject.meshBiomarkers-
dc.subject.meshBreath Tests-
dc.subject.meshCase-Control Studies-
dc.subject.meshChild-
dc.subject.meshChild, Preschool-
dc.subject.meshMinor Surgical Procedures-
dc.subject.meshNitric Oxide-
dc.subject.meshPredictive Value of Tests-
dc.subject.meshPreoperative Care-
dc.subject.meshRespiration Disorders-
dc.subject.meshPostoperative Complications-
dc.titlePrediction of peri-operative adverse respiratory events in children: the role of exhaled nitric oxide.-
dc.typeEvaluation Studies-
dc.typeJournal Article-
dc.typeResearch Support, Non-U.S. Gov't-
dc.identifier.journaltitleAnaesthesia-
dc.identifier.doi10.1111/anae.13123-
dc.description.pubmedurihttps://www.ncbi.nlm.nih.gov/pubmed/26032864-
dc.identifier.pubmedid26032864-
dc.ispartof.anzcaresearchfoundationYes-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.cerifentitytypePublications-
item.cerifentitytypePublications-
item.openairetypeEvaluation Studies-
item.openairetypeJournal Article-
item.openairetypeResearch Support, Non-U.S. Gov't-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
Appears in Collections:Scholarly and Clinical
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