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Please use this identifier to cite or link to this item: http://hdl.handle.net/11055/1119
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dc.contributor.authorBinks, MJen_US
dc.contributor.authorHolyoak, RSen_US
dc.contributor.authorMelhuish, TMen_US
dc.contributor.authorVlok, Ren_US
dc.contributor.authorBond, Een_US
dc.contributor.authorWhite, LDen_US
dc.date2017-06-24-
dc.date.accessioned2021-12-21T04:16:45Z-
dc.date.available2021-12-21T04:16:45Z-
dc.date.issued2017-10-
dc.identifier.citation35(10):1542-1546.en_US
dc.identifier.issn0735-6757en_US
dc.identifier.urihttp://hdl.handle.net/11055/1119-
dc.description.abstractBackground: Hypoxemia increases the risk of intubation markedly. Such concerns are multiplied in the emergency department (ED) and during retrieval where patients may be unstable, preparation or preoxygenation time limited and the environment uncontrolled. Apneic oxygenation is a promising means of preventing hypoxemia in this setting. Aim: To test the hypothesis that apnoeic oxygenation reduces the incidence of hypoxemia during endotracheal intubation in the ED and during retrieval. Methods: We undertook a systematic review of six databases for all relevant studies published up to November 2016. Included studies evaluated apneic oxygenation during intubation in the ED and during retrieval. There were no exemptions based on study design. All studies were assessed for level of evidence and risk of bias. The Review Manager 5.3 software was used to perform meta-analysis of the pooled data. Results: Six trials and a total 1822 cases were included for analysis. The study found a significant reduction in the incidence of desaturation (RR=0.76, p=0.002) and critical desaturation (RR=0.51, p=0.01) when apneic oxygenation was implemented. There was also a significant improvement in first pass intubation success rate (RR=1.09, p=0.004). Conclusion: Apneic oxygenation may reduce patient hypoxemia during intubation performed in the ED and during retrieval. It also improves intubation first-pass success rate in this setting.en_US
dc.subjectAirway Extubation / methodsen_US
dc.subjectApnea / therapyen_US
dc.subjectEmergency Service, Hospitalen_US
dc.subjectHumansen_US
dc.subjectHypoxia / prevention & controlen_US
dc.subjectIntubation, Intratracheal / methodsen_US
dc.subjectOxygen Inhalation Therapy / methodsen_US
dc.subjectRespiration, Artificial / methodsen_US
dc.titleApneic oxygenation during intubation in the emergency department and during retrieval: A systematic review and meta-analysisen_US
dc.typeJournal Articleen_US
dc.type.contentTexten_US
dc.identifier.journaltitleThe American journal of emergency medicine.en_US
dc.identifier.doi10.1016/j.ajem.2017.06.046.en_US
dc.description.affiliatesWagga Wagga Rural Referral Hospital, NSW, Australiaen_US
dc.description.affiliatesSchool of Medicine, University of Wollongong, NSW, Australiaen_US
dc.description.pubmedurihttps://pubmed.ncbi.nlm.nih.gov/28684195/en_US
dc.type.studyortrialReviews/Systematic Reviewsen_US
dc.contributor.anzcaWhite, LDen_US
Appears in Collections:Scholarly and Clinical

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