AIRR - ANZCA Institutional Research Repository
Skip navigation
Please use this identifier to cite or link to this item: https://hdl.handle.net/11055/1023
Full metadata record
DC FieldValueLanguage
dc.contributor.authorYoung, Jen_US
dc.contributor.authorZoghi, Men_US
dc.contributor.authorKhan, Fen_US
dc.contributor.authorGalea, MPen_US
dc.date2020-06-28-
dc.date.accessioned2020-10-15T04:52:40Z-
dc.date.available2020-10-15T04:52:40Z-
dc.date.issued2020-06-28-
dc.identifier.issn1526-2375en_US
dc.identifier.urihttp://hdl.handle.net/11055/1023-
dc.description.abstractObjective: Chronic neuropathic pain is a common symptom in multiple sclerosis (MS). This randomized controlled single-blinded study investigated whether a new protocol involving five days of transcranial direct current stimulation (tDCS) with an interval period would be effective to reduce pain using the visual analog scale (VAS). Other secondary outcomes included the Neuropathic Pain Scale (NPS), Depression Anxiety Stress Score (DASS), Short Form McGill Pain Questionnaire (SFMPQ), and Multiple Sclerosis Quality of Life 54 (MSQOL54). Design: A total of 30 participants were recruited for the study, with 15 participants randomized to a sham group or and 15 randomized to an active group. After a five-day course of a-tDCS, VAS and NPS scores were measured daily and then weekly after treatment up to four weeks after treatment. Secondary outcomes were measured pretreatment and then weekly up to four weeks. Results: After a five-day course of a-tDCS, VAS scores were significantly reduced compared with sham tDCS and remained significantly low up to week 2 post-treatment. There were no statistically significant mean changes in MSQOL54, SFMPQ, NPS, or DASS for the sham or treatment group before treatment or at four-week follow-up. Conclusions: This study shows that repeated stimulation with a-tDCS for five days can reduce pain intensity for a prolonged period in patients with MS who have chronic neuropathic pain.en_US
dc.subjectChronic Painen_US
dc.subjectMultiple sclerosisen_US
dc.subjectNeuromodulationen_US
dc.subjectNeuropathic painen_US
dc.subjectNonpharmacological interventionsen_US
dc.titleThe effect of transcranial direct current stimulation on chronic neuropathic pain in patients with multiple sclerosis: randomized controlled trialen_US
dc.typeJournal Articleen_US
dc.type.contentTexten_US
dc.identifier.journaltitlePain Medicineen_US
dc.identifier.doi10.1093/pm/pnaa128en_US
dc.description.affiliatesRoyal Melbourne Hospitalen_US
dc.description.affiliatesUniversity of Melbourneen_US
dc.description.affiliatesLa Trobe Universityen_US
dc.description.pubmedurihttps://pubmed.ncbi.nlm.nih.gov/32594139/en_US
dc.type.studyortrialStudyen_US
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.cerifentitytypePublications-
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
Appears in Collections:Scholarly and Clinical
Show simple item record

Page view(s)

24
checked on Mar 28, 2024

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.