Please use this identifier to cite or link to this item:
https://hdl.handle.net/11055/603
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Story, DA | en_US |
dc.contributor.author | Leslie, K | en_US |
dc.contributor.author | Myles, PS | en_US |
dc.contributor.author | Fink, M | en_US |
dc.contributor.author | Poustie, SJ | en_US |
dc.contributor.author | Forbes, A | en_US |
dc.contributor.author | Yap, S | en_US |
dc.contributor.author | Beavis, V | en_US |
dc.contributor.author | Kerridge, R | en_US |
dc.contributor.author | REASON Investigators | en_US |
dc.contributor.author | ANZCA Clinical Trials Network | en_US |
dc.date.accessioned | 2018-06-20T03:34:58Z | - |
dc.date.available | 2018-06-20T03:34:58Z | - |
dc.date.issued | 2010-10 | - |
dc.identifier.citation | 5(10):1022-30. | en_US |
dc.identifier.uri | http://hdl.handle.net/11055/603 | - |
dc.description.abstract | We conducted a prospective study of non-cardiac surgical patients aged 70 years or more in 23 hospitals in Australia and New Zealand. We studied 4158 consecutive patients of whom 2845 (68%) had pre-existing comorbidities. By day 30, 216 (5%) patients had died, and 835 (20%) suffered complications; 390 (9.4%) patients were admitted to the Intensive Care Unit. Pre-operative factors associated with mortality included: increasing age (80-89 years: OR 2.1 (95% CI 1.6-2.8), p < 0.001; 90+ years: OR 4.0 (95% CI 2.6-6.2), p < 0.001); worsening ASA physical status (ASA 3: OR 3.1 (95% CI 1.8-5.5), p < 0.001; ASA 4: OR 12.4 (95% CI 6.9-22.2), p < 0.001); a pre-operative plasma albumin < 30 g.l⁻¹ (OR: 2.5 (95% CI 1.8-3.5), p < 0.001); and non-scheduled surgery (OR 1.8 (95% CI 1.3-2.5), p < 0.001). Complications associated with mortality included: acute renal impairment (OR 3.3 (95% CI 2.1-5.0), p < 0.001); unplanned Intensive Care Unit admission (OR 3.1 (95% CI 1.9-4.9), p < 0.001); and systemic inflammation (OR 2.5 (95% CI 1.7-3.7), p < 0.001). Patient factors often had a stronger association with mortality than the type of surgery. Strategies are needed to reduce complications and mortality in older surgical patients. | en_US |
dc.title | Complications and mortality in older surgical patients in Australia and New Zealand (the REASON study): a multicentre, prospective, observational study. | en_US |
dc.type | Journal Article | en_US |
dc.type.content | Text | en_US |
dc.identifier.journaltitle | Anaesthesia | en_US |
dc.identifier.doi | 10.1111/j.1365-2044.2010.06478.x. | en_US |
dc.description.affiliates | Austin Health | en_US |
dc.description.pubmeduri | https://www.ncbi.nlm.nih.gov/pubmed/20731639 | en_US |
dc.type.studyortrial | Multicentre Studies | en_US |
dc.identifier.studyname | The REASON study | en_US |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.openairetype | Journal Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
Appears in Collections: | Scholarly and Clinical |
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