AIRR - ANZCA Institutional Research Repository
Skip navigation
Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorSilbert, Brendan-
dc.contributor.authorEvered, Lisbeth-
dc.contributor.authorScott, David A-
dc.contributor.authorMcMahon, Stephen-
dc.contributor.authorChoong, Peter-
dc.contributor.authorAmes, David-
dc.contributor.authorMaruff, Paul-
dc.contributor.authorJamrozik, Konrad-
dc.identifier.citationAnesthesiology 2015-06; 122(6): 1224-34-
dc.description.abstractThis study investigated the prevalence of cognitive impairment in elderly noncardiac surgery patients and any association between preoperative cognitive impairment and postoperative cognitive dysfunction (POCD). Additionally, the incidence of cognitive decline at 12 months after surgery was identified. Three hundred patients for hip joint replacement and 51 nonsurgical controls aged 60 yr or older were studied in a prospective observational clinical trial. All study participants and controls completed a battery of eight neuropsychological tests before surgery and at 7 days, 3 months, and 12 months afterwards. Preoperative cognitive status was assessed using preexisting cognitive impairment (PreCI) defined as a decline of at least 2 SD on two or more of seven neuropsychological tests compared to population norms. POCD and cognitive decline were assessed using the reliable change index utilizing the results of the control group. PreCI was classified in 96 of 300 (32%) patients (95% CI, 23 to 43%). After surgery, 49 of 286 (17%) patients (95% CI, 13 to 22%) and 27 of 284 (10%) patients (95% CI, 6 to 13%) demonstrated POCD at 7 days and 3 months, respectively, while 7 of 271 (3%) patients (95% CI, 1 to 4%) demonstrated cognitive decline at 12 months. Patients with PreCI had a significantly increased incidence of POCD at 7 days and 3 months and cognitive decline at 12 months. Patients with PreCI have an increased incidence of POCD and cognitive decline. PreCI is a good predictor of subsequent POCD and cognitive decline. The incidence of cognitive decline after 12 months in this group of patients is low.-
dc.subject.meshAged, 80 and over-
dc.subject.meshArthroplasty, Replacement, Hip-
dc.subject.meshCognition Disorders-
dc.subject.meshConsciousness Monitors-
dc.subject.meshDisease Progression-
dc.subject.meshMiddle Aged-
dc.subject.meshNeuropsychological Tests-
dc.subject.meshPostoperative Complications-
dc.subject.meshProspective Studies-
dc.subject.meshPreexisting Condition Coverage-
dc.titlePreexisting cognitive impairment is associated with postoperative cognitive dysfunction after hip joint replacement surgery.-
dc.typeJournal Article-
dc.typeObservational Study-
dc.typeResearch Support, Non-U.S. Gov't-
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
item.openairetypeObservational Study-
item.openairetypeResearch Support, Non-U.S. Gov't-
Appears in Collections:Scholarly and Clinical
Show simple item record

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.