AIRR - ANZCA Institutional Research Repository
Skip navigation
Please use this identifier to cite or link to this item: https://hdl.handle.net/11055/271
Full metadata record
DC FieldValueLanguage
dc.contributor.authorWen, Syb-
dc.contributor.authorPeng, Azy-
dc.contributor.authorBoyle, S-
dc.contributor.authorCai, S-
dc.contributor.authorPope, L-
dc.contributor.authorTran, MT-
dc.contributor.authorShort, TG-
dc.contributor.authorAneman, A-
dc.contributor.authorJaeger, M-
dc.contributor.authorChuan, A-
dc.date.accessioned2018-03-08T22:25:26Z-
dc.date.available2018-03-08T22:25:26Z-
dc.date.issued2017-
dc.identifier.citationAnaesthesia and intensive care 2017; 45(2): 202-209-
dc.identifier.issn0310-057X-
dc.identifier.urihttp://hdl.handle.net/11055/271-
dc.description.abstractThis prospective pilot study evaluated whether low preoperative cerebral tissue oxygen saturation is associated with unfavourable outcomes after major elective non-cardiac surgery. Eighty-one patients over 60 years of age, American Society of Anesthesiologists physical status 3 or 4, were recruited. Resting cerebral tissue oxygen saturation was recorded on room air, and after oxygen supplementation, using cerebral oximetry. The primary outcome was 30-day major adverse event of combined mortality or severe morbidity, and the secondary outcome was 30-day new disability. Eleven patients (13.6%) suffered a major adverse event, and 28 patients (34.6%) experienced new disability. Room air cerebral tissue oxygen saturation was significantly different between patients who had a major adverse event, 67% (95% confidence interval [CI] 65-70) versus unaffected, 71% (95% CI 70-72;P=0.04). No statistical difference was found between patients for new disability (range 70%-74%;P=0.73). Room air cerebral tissue oxygen saturation was significantly associated with major adverse events (odds ratio 1.36 (95% CI 1.03-1.79),P=0.03). Saturation levels ≤68% carried a positive likelihood ratio of 2.2 for death or severe morbidity,P=0.04. A definitive trial is required to confirm if cerebral oximetry can be used to stratify the cardiovascular risk of patients presenting for non-cardiac surgery.-
dc.language.isoeng-
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshBrain-
dc.subject.meshCardiovascular Diseases-
dc.subject.meshOxygen-
dc.subject.meshPilot Projects-
dc.subject.meshPostoperative Complications-
dc.subject.meshProspective Studies-
dc.subject.meshRisk Factors-
dc.titleA pilot study using preoperative cerebral tissue oxygen saturation to stratify cardiovascular risk in major non-cardiac surgery.-
dc.typeJournal Article-
dc.identifier.journaltitleAnaesthesia and intensive care-
dc.description.pubmedurihttps://www.ncbi.nlm.nih.gov/pubmed/28267942-
dc.identifier.pubmedid28267942-
dc.ispartof.anzcaresearchfoundationYes-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
Appears in Collections:Scholarly and Clinical
Show simple item record

Page view(s)

42
checked on Mar 28, 2024

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.