Please use this identifier to cite or link to this item:
https://hdl.handle.net/11055/247
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Story, DA | - |
dc.contributor.author | Leslie, K | - |
dc.contributor.author | Myles, PS | - |
dc.contributor.author | Fink, M | - |
dc.contributor.author | Poustie, S J | - |
dc.contributor.author | Forbes, A | - |
dc.contributor.author | Yap, S | - |
dc.contributor.author | Beavis, V | - |
dc.contributor.author | Kerridge, R | - |
dc.contributor.author | REASON Investigators | - |
dc.contributor.author | Australian and New Zealand College of Anaesthetists Trials Group | - |
dc.date.accessioned | 2018-03-08T02:32:19Z | - |
dc.date.available | 2018-03-08T02:32:19Z | - |
dc.date.issued | 2010-10 | - |
dc.identifier.citation | Anaesthesia 2010-10; 65(10): 1022-30 | - |
dc.identifier.uri | http://hdl.handle.net/11055/247 | - |
dc.description.abstract | We conducted a prospective study of non-cardiac surgical patients aged 70 years or more in 23 hospitals in Australia and New Zealand. We studied 4158 consecutive patients of whom 2845 (68%) had pre-existing comorbidities. By day 30, 216 (5%) patients had died, and 835 (20%) suffered complications; 390 (9.4%) patients were admitted to the Intensive Care Unit. Pre-operative factors associated with mortality included: increasing age (80-89 years: OR 2.1 (95% CI 1.6-2.8), p < 0.001; 90+ years: OR 4.0 (95% CI 2.6-6.2), p < 0.001); worsening ASA physical status (ASA 3: OR 3.1 (95% CI 1.8-5.5), p < 0.001; ASA 4: OR 12.4 (95% CI 6.9-22.2), p < 0.001); a pre-operative plasma albumin < 30 g.l⁻¹ (OR: 2.5 (95% CI 1.8-3.5), p < 0.001); and non-scheduled surgery (OR 1.8 (95% CI 1.3-2.5), p < 0.001). Complications associated with mortality included: acute renal impairment (OR 3.3 (95% CI 2.1-5.0), p < 0.001); unplanned Intensive Care Unit admission (OR 3.1 (95% CI 1.9-4.9), p < 0.001); and systemic inflammation (OR 2.5 (95% CI 1.7-3.7), p < 0.001). Patient factors often had a stronger association with mortality than the type of surgery. Strategies are needed to reduce complications and mortality in older surgical patients. | - |
dc.language.iso | eng | - |
dc.subject.mesh | Acute Kidney Injury | - |
dc.subject.mesh | Age Factors | - |
dc.subject.mesh | Aged | - |
dc.subject.mesh | Aged, 80 and over | - |
dc.subject.mesh | Australia | - |
dc.subject.mesh | Comorbidity | - |
dc.subject.mesh | Emergencies | - |
dc.subject.mesh | Epidemiologic Methods | - |
dc.subject.mesh | Inflammation | - |
dc.subject.mesh | Length of Stay | - |
dc.subject.mesh | New Zealand | - |
dc.subject.mesh | Postoperative Complications | - |
dc.subject.mesh | Serum Albumin | - |
dc.subject.mesh | Sex Factors | - |
dc.subject.mesh | Surgical Procedures, Operative | - |
dc.title | Complications and mortality in older surgical patients in Australia and New Zealand (the REASON study): a multicentre, prospective, observational study. | - |
dc.type | Journal Article | - |
dc.type | Multicenter Study | - |
dc.type | Research Support, Non-U.S. Gov't | - |
dc.identifier.journaltitle | Anaesthesia | - |
dc.identifier.doi | 10.1111/j.1365-2044.2010.06478.x | - |
dc.description.pubmeduri | https://www.ncbi.nlm.nih.gov/pubmed/20731639 | - |
dc.identifier.pubmedid | 20731639 | - |
dc.ispartof.anzcaresearchfoundation | Yes | - |
item.openairetype | Journal Article | - |
item.openairetype | Multicenter Study | - |
item.openairetype | Research Support, Non-U.S. Gov't | - |
item.cerifentitytype | Publications | - |
item.cerifentitytype | Publications | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
Appears in Collections: | Scholarly and Clinical |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.