AIRR - ANZCA Institutional Research Repository
Skip navigation
Please use this identifier to cite or link to this item: https://hdl.handle.net/11055/610
Full metadata record
DC FieldValueLanguage
dc.contributor.authorDaly, DJen_US
dc.contributor.authorMyles, PSen_US
dc.contributor.authorSmith, JAen_US
dc.contributor.authorKnight, JLen_US
dc.contributor.authorClavisi, Oen_US
dc.contributor.authorBain, DLen_US
dc.contributor.authorGlew, Ren_US
dc.contributor.authorGibbs, NMen_US
dc.contributor.authorMerry, AEen_US
dc.contributor.authorANZCA Clinical Trials Networken_US
dc.date.accessioned2018-06-20T03:46:10Z-
dc.date.available2018-06-20T03:46:10Z-
dc.date.issued2007-10-
dc.identifier.citation35(5):760-8.en_US
dc.identifier.urihttp://hdl.handle.net/11055/610-
dc.description.abstractWe surveyed contemporary Australasian cardiac surgical and anaesthetic practice, focusing on antiplatelet and antifibrinolytic therapies and blood transfusion practices. The cohort included 499 sequential adult cardiac surgical patients in 12 Australasian teaching hospitals. A total of 282 (57%) patients received red cell or component transfusion. The median (IQR) red cell transfusion threshold haemogloblin levels were 66 (61-73) g/l intraoperatively and 79 (74-85) g/l postoperatively. Many (40%) patients had aspirin within five days of surgery but this was not associated with blood loss or transfusion; 15% had clopidogrel within seven days of surgery. In all, 30 patients (6%) required surgical re-exploration for bleeding. Factors associated with transfusion and excessive bleeding include pre-existing renal impairment, preoperative clopidogrel therapy, and complex or emergency surgery. Despite frequent (67%) use of antifibrinolytic therapy, there was a marked variability in red cell transfusion rates between centres (range 17 to 79%, P < 0.001). This suggests opportunities for improvement in implementation of guidelines and effective blood-sparing interventions. Many patients presenting for surgery receive antiplatelet and/or antifibrinolytic therapy, yet the subsequent benefits and risks remain unclear.en_US
dc.titleAnticoagulation, bleeding and blood transfusion practices in Australasian cardiac surgical practice.en_US
dc.typeJournal Articleen_US
dc.type.contentTexten_US
dc.identifier.journaltitleAnaesthesia and Intensive Careen_US
dc.description.pubmedurihttps://www.ncbi.nlm.nih.gov/pubmed/17933164en_US
dc.type.studyortrialSurveyen_US
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.cerifentitytypePublications-
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
Appears in Collections:Scholarly and Clinical
Show simple item record

Page view(s)

62
checked on Mar 28, 2024

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.